The Top 5 Deadliest Diseases

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The Top 5 Deadliest Diseases

1. Ischemic heart disease, or coronary artery disease

The deadliest disease in the world is coronary artery disease (CAD). Also called ischemic heart disease, CAD occurs when the blood vessels that supply blood to the heart become narrowed. Untreated CAD can lead to chest pain, heart failure, and arrhythmias.


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Impact of CAD across the world


HealthGrove | Graphiq
Although it’s still the leading cause of death, mortality rates have declined in many European countries and in the United States. This may be due to better public health education, access to healthcare, and forms of prevention. However, in many developing nations, mortality rates of CAD are on the rise. An increasing life span, socioeconomic changes, and lifestyle risk factors play a role in this rise.

Risk factors and prevention

Risk factors for CAD include:
  • high blood pressure
  • high cholesterol
  • smoking
  • family history of CAD
  • diabetes
  • being overweight
Talk to your doctor if you have one or more of these risk factors.
You can prevent CAD with medications and by maintaining good heart health. Some steps you can take to decrease your risk include:
  • exercising regularly
  • maintaining a healthy weight
  • eating a balanced diet that’s low in sodium and high in fruits and vegetables
  • avoiding smoking
  • drinking only in moderation
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2. Stroke

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A stroke occurs when an artery in your brain is blocked or leaks. This causes the oxygen-deprived brain cells to begin dying within minutes. During a stroke, you feel sudden numbness and confusion or have trouble walking and seeing. If left untreated, a stroke can cause long-term disability.
In fact, strokes are the leading cause of long-term disabilities. People who receive treatment within 3 hours of having a stroke are less likely to have disabilities. The Centers for Disease Control and Prevention (CDC) reports that 93 percent of people knew sudden numbness on one side was a stroke symptom. But only 38 percent knew all the symptoms that would prompt them to seek emergency care.

Risk factors and prevention

Risk factors for stroke include:
  • high blood pressure
  • family history of stroke
  • smoking, especially when combined with oral contraceptives
  • being African-American
  • being female
Some risk factors of strokes can be reduced with preventative care, medications, and lifestyle changes. In general, good health habits can lower your risk.
Stroke prevention methods may include controlling high blood pressure with medications or surgery. You should also maintain a healthy lifestyle, complete with regular exercise and a healthy diet that’s low in sodium. Avoid smoking, and drink only in moderation, as these activities increase your risk of stroke.
Part 4 of 12

3. Lower respiratory infections

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A lower respiratory infection is an infection in your airways and lungs. It can be due to:
  • influenza, or the flu
  • pneumonia
  • bronchitis
  • tuberculosis
Viruses usually cause lower respiratory infections. They can also be caused by bacteria. Coughing is the main symptom of a lower respiratory infection. You may also feel breathlessness, wheezing, and a tight feeling in your chest. Untreated lower respiratory infections can lead to breathing failure and death.

Impact of lower respiratory infections around the world


HealthGrove | Graphiq

Risk factors and prevention

Risk factors for lower respiratory infection include:
  • the flu
  • poor air quality or frequent exposure to lung irritants
  • smoking
  • a weak immune system
  • crowded childcare settings, which mainly affects infants
  • asthma
  • HIV
One of the best preventative measures you can take against lower respiratory infections is to get the flu shot every year. People at high risk of pneumonia can also get a vaccine. Wash your hands regularly with soap and water to avoid transmitted bacteria, especially before touching your face and before eating. Stay at home and rest until you feel better if you have a respiratory infection, as rest improves healing.
Part 5 of 12

4. Chronic obstructive pulmonary disease

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Chronic obstructive pulmonary disease (COPD) is a long-term, progressive lung disease that makes breathing difficult. Chronic bronchitis and emphysema are types of COPD. In 2004, about 64 million people around the world were living with COPD.

Impact of COPD around the world


HealthGrove | Graphiq

Risk factors and prevention

Risk factors for COPD include:
  • smoking or secondhand smoke
  • lung irritants like chemical fumes
  • family history, with the AATD gene being linked to COPD
  • history of respiratory infections as a child
There’s no cure for COPD, but its progression can be slowed with medication. The best ways to prevent COPD are to stop smoking and to avoid secondhand smoke and other lung irritants. If you experience any COPD symptoms, getting treatment as soon as possible increases your outlook.

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